protection • prophylactic • therapy

4809 Kcal/kg

HyperSen

TO MANAGE
FOOD ALLERGY AND
ATOPIC SKIN DISEASES

Hydrolysed proteins
Urinary pH control
(EPA+DHA) + Borage oil
Natural antioxidant mixture
Prebiotics
F.H.V. / F.L.V.
Odour control

Indication

The combined characteristics of PRO-VET HYPERSEN makes this ration useful in the treatment of various canine disorders. Food hypersensitivity and atopy often co-exist in cats and it is difficult to distinguish definitively between the two conditions. PRO-VET HYPERSEN makes it possible to treat both patients with food hypersensitivity and those with atopy.
Chopping proteins into smaller peptide fragments decreases their antigenicity. This principle extends to cats with food hypersensitivity. Cats with hypersensitivity towards soy protein developed pruritis upon ingesting the intact protein, but did not do so with hydrolysed soy protein.
PRO-VET HYPERSEN is hypoallergenic diet which contains hydrolysed proteins which have been used as elimination diet. So far elimination diets with hydrolysed and parent proteins have not been compared directly, but based on data for elimination diets with intact and hydrolysed proteins it could be suggested that hypoallergenic diets as PRO-VET HYPERSEN with hydrolysed proteins is more effective than those with intact proteins in the management of food hypersensitivity.

Atopy and food hypersensitivity often go hand in hand and have similar clinical signs, but skin disorders caused by inhaled allergens will not react to hypoallergenic protein sources. The treatment of atopic dermatitis involves the suppression of chronic inflammatory reactions in the skin. PRO-VET HYPERSEN contents eicosanoids formed from di-homo-gamma linolenic acid and from eicosapentaenoic acid (EPA) so that PRO-VET HYPERSEN has an anti-inflammatory properties.

Double blind, placebo-controlled experiments in cats with atopic dermatitis have shown that supplements of both borage oil, which is rich in gamma-linolenic acid (GLA) and fish oil, which is rich in EPA, lower the severity of pruritis, erythema and self-trauma. Good results have been obtained with a diet rich in both fish oil and borage oil. PRO-VET HYPERSEN contains about 0.5% borage oil and 5% fish oil. The efficiancy of PRO-VET HYPERSEN was tested in four clinics using a double blind, placebo-controlled design. After 10 weeks on the diet, the scores for pruritis and erythema had decreased to about half, while the control treatment had no influence. According to the owners the diet had improved skin condition by 60% of the cats. Clearly, a substantial number of the patients with atopic dermatitis will improve after feeding PRO-VET HYPERSEN enriched with suitable amounts of fish oil and borage oil. However, there will be great differences in individual responsiveness.

By cats with idiopathic chronic colitis or inflammatory bowel disease, the feeding of a hypoallergenic diet as PRO-VET HYPERSEN based on a hydrolysed protein source caused a significant decrease in clinical signs. Ingestion of fish oil may be expected to further improve the clinical condition through its anti-inflammatory activity. By humans with ulcerative colitis such a positive effect has been demonstrated.

Efficacy

CHARACTERISTIC	EFFECT
Hydrolysed protein sources	Prevention of adverse reactions to food
Added salmon oil 5%	Anti-inflammatory action, anti-cachectic action
Added borage oil 0.5%	Lowers the severity of pruritus, erythema and self-trauma. It has anti-inflammatory activity and thereby controls skin conditions such as atopic dermatitis. The active principle of borage oil is the omega-6 fatty acid, gamma-linolenic acid (GLA).
High digestibility of proteins, fats and carbohydrates	Good consistency of faeces
Rich in polyunsaturated fatty acids of the omega-3 family (EPA+DHA)	Stimulation of immune function. Improvement of condition of skin in atopic disease. Diminishes risk of cancer, kidney failure and osteoarthritis
Steering of urinary acidity and lowering of the concentrations of struvite-forming components	Reduction of the risk of struvite formation
Rich in natural antioxidants	Reduces risk of cancer and renal insufficiency
Low in phosphorus	Less risk of renal failure
Added Yucca extract	Diminishes odour formation by faeces
Added prebiotics: mannan oligosaccharides fructo oligosaccharides	Supports the growth of beneficial bacteria in the intestine. Encourages peristaltic motion, exerting a positive influence on bowel activity and evacuation.

Composition

rice, hydrolysed fish protein, potato protein, animal fat, salmon oil, dried beet pulp, dehydrated potato protein, hydrolysed soya protein isolate, purified vegetable fibre (cellulose), hydrolysed chicken liver, monocalcium phosphate, calcium carbonate, potassium chloride, mannan oligosaccharides, borage seed oil (Borago Officinalis), amoniumchloride, linseed oil, L-cartnitine, taurine, inulin (source of fructo oligosaccharides), Yucca Schidigera extract, rosemary extract.

*With oxidation reducing substance tocopherol-rich extract of natural originl (vitamin E) and preservatives citric acid, calcium propionate and sorbic acid, permitted by the EU.

Analyses

Analyses/kg:		Added/kg:
Moisture Crude protein Crude fat Crude ash Crude fibre Calcium (Ca) Phosphorus (P) Sodium (Na) Magnesium (Mg) Potassium Lysine Methionine Cystine Treonine Tryptophan Linoleic acid (W6) Linolenic acid (W3) Arachidonic acid (W6) EPA (W3) eicosapentaenoic acid DHA (W3) docosahexaenoic acid Carbohydrates Iron (Fe) Manganese (Mn) Copper (Cu)* Zinc (Zn) Iodine (I) Selenium (Se)	9 % 32 % 20 % 5.3 % 2.5 % 0.6 g 0.6 g 3.6 g 0.6 g 6 g 20 g 8 g 3.9 g 14.6 g 3.4 g 19 g 4 g 0.6 g 5.0 g 5.0 g 0.9 g 31.2% 100 mg 40 mg 5.0 mg 150 mg 1.0 mg 0.20 mg	Vitamin A Vitamin D3 Vitamin E* Vitamin B1 Vitamin B2 Vitamin B6 Vitamin B12 Vitamin C Vitamin K3* Biotin Cholin Folic acid Ca. pantothenate Taurine Inulin L-carnitine M.O.S.	16.500 IE 1.650 IE 600 mg 7.5 mg 5.6 mg 6 mg 30 mcg 350 mg 0.8 mg 225 mcg 750 mg 9 mg 23 mg 1.150 mg 500 mg 750 mg 500 mg

Energy 4809 Kcal/kg
pH urinary = ca 6,3

* vitamin E (alpha-tocopherol)
* vitamin K3 (menadione-nicotinamide-bisulfite)
* copper (Cu) (cupric sulphate II pentahydrate)

Feeding guide

Body weight	Daily portion
2 kg	30 - 40 g
3 kg	40 - 55 g
4 kg	50 - 70 g
5 kg	60 - 85 kg
>6 kg	10 - 15 g/kg

The recommended duration of feeding this diet is 3 to 8 weeks; if the signs disappear this feed can be used indefinitely.

Verpakking

3kg